Katrina is responsible for approximately 1200 reported deaths, including about 1000 in Louisiana and 200 in Mississippi. Seven additional deaths occurred in southern Florida. Katrina caused catastrophic damage in southeastern Louisiana and southern Mississippi.

Storm surge along the Mississippi coast caused total destruction of many structures, with the surge damage extending several miles inland. Similar damage occurred in portions of southeastern Louisiana southeast of New Orleans.

The surge overtopped and breached levees in the New Orleans metropolitan area, resulting in the inundation of much of the city and its eastern suburbs. Wind damage from Katrina extended well inland into northern Mississippi and Alabama. The hurricane also caused wind and water damage in Miami-Dade and Broward counties. annually.